Comparison between Silver Diamine Fluoride and Fluoride Varnish on their Ability to Reduce Streptococcus mutans Levels and Caries Progression among Thai Preschool Children
Keywords:
Early Childhood Caries, S. mutans, Silver Diamine Fluoride, Fluoride Varnish, Arrested Caries, ICDAS SystemAbstract
Objective: To compare the effectiveness of silver diamine fluoride (SDF) and sodium fluoride (NaF) varnish in stopping caries progression and effects on S. mutans level. Materials and Methods: Ninety-one children aged 2-5 years old were selected and divide into 3 groups: 29 in Group 1-treated with 38% SDF, 31 in Group 2-treated with 5% NaF varnish and 31 in Group 3-control group. Dental caries was assessed using ICDAS scoring system. Supra gingiva plaque was collected at 1, 3 and 6 months visits. DNA was extracted and performed realtime PCR to quantify amount of S. mutans. Results: At 6 months, 69 subjects were remained, 22 in Group 1 and 3, 25 in Group 2. Mean age was 4.2 ± 0.96 years. Only in Group 1, S. mutans levels were different between baseline to 3 months (p = 0.031), and 3 months to 6 months (p = 0.035). At 1-, 3- and 6-month examination, total number of arrested surface scores in Group 1 was higher than Group 2 and 3 at all follow-up visits (p < 0.001). Arrested surface scores at anterior and posterior teeth in Group 1 were higher than in Group 2 and 3 at 3- and 6-month follow-up visits (p < 0.001). The progression rate of current caries lesions in Group 1 was lower than in Group 2 and 3 at the 6 months examination (p < 0.001). Conclusion: S. mutans levels in SDF group were different between baseline to 3 months, and 3 to 6 months. SDF was more effective than NaF in stop caries progression.Downloads
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