Comparison between Silver Diamine Fluoride and Fluoride Varnish on their Ability to Reduce Streptococcus mutans Levels and Caries Progression among Thai Preschool Children

Authors

  • Russarin Suthiratanasopob Section of Dental Public Health, Division of Public Health and Environment, Prachuap Khiri Khan Town Municipality, Prachuap Khiri Khan 77000, Thailand
  • Yuwadee Asvanund Department of Pediatric Dentistry, Faculty of Dentistry, Mahidol University, 6, Yothi Road, Ratchathewi District, Bangkok 10400, Thailand
  • Kemthong Mitrakul Department of Pediatric Dentistry, Faculty of Dentistry, Mahidol University, 6, Yothi Road, Ratchathewi District, Bangkok 10400, Thailand.

Keywords:

Early Childhood Caries, S. mutans, Silver Diamine Fluoride, Fluoride Varnish, Arrested Caries, ICDAS System

Abstract

Objective: To compare the effectiveness of silver diamine fluoride (SDF) and sodium fluoride (NaF) varnish in stopping caries progression and effects on S. mutans level. Materials and Methods: Ninety-one children aged 2-5 years old were selected and divide into 3 groups: 29 in Group 1-treated with 38% SDF, 31 in Group 2-treated with 5% NaF varnish and 31 in Group 3-control group. Dental caries was assessed using ICDAS scoring system. Supra gingiva plaque was collected at 1, 3 and 6 months visits. DNA was extracted and performed realtime PCR to quantify amount of S. mutans. Results: At 6 months, 69 subjects were remained, 22 in Group 1 and 3, 25 in Group 2. Mean age was 4.2 ± 0.96 years. Only in Group 1, S. mutans levels were different between baseline to 3 months (p = 0.031), and 3 months to 6 months (p = 0.035). At 1-, 3- and 6-month examination, total number of arrested surface scores in Group 1 was higher than Group 2 and 3 at all follow-up visits (p < 0.001). Arrested surface scores at anterior and posterior teeth in Group 1 were higher than in Group 2 and 3 at 3- and 6-month follow-up visits (p < 0.001). The progression rate of current caries lesions in Group 1 was lower than in Group 2 and 3 at the 6 months examination (p < 0.001). Conclusion: S. mutans levels in SDF group were different between baseline to 3 months, and 3 to 6 months. SDF was more effective than NaF in stop caries progression.

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Author Biography

Yuwadee Asvanund, Department of Pediatric Dentistry, Faculty of Dentistry, Mahidol University, 6, Yothi Road, Ratchathewi District, Bangkok 10400, Thailand

correspondence

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Published

2023-09-13

How to Cite

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Suthiratanasopob R, Asvanund Y, Mitrakul K. Comparison between Silver Diamine Fluoride and Fluoride Varnish on their Ability to Reduce Streptococcus mutans Levels and Caries Progression among Thai Preschool Children. SWU Dent J. [Internet]. 2023 Sep. 13 [cited 2024 Dec. 11];16(2):83-98. Available from: https://ejournals.swu.ac.th/index.php/swudentj/article/view/15450

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บทวิทยาการ (Original articles)

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