ปัจจัยทำนายคุณภาพชีวิตด้านสุขภาพในผู้ป่วยโรคลำไส้อักเสบ Factors Predicting Health-Related Quality of Life in Patients with Inflammatory Bowel Disease
Abstract
บทคัดย่อ วัตถุประสงค์: เพื่อประเมินระดับคุณภาพชีวิตที่เกี่ยวข้องกับสุขภาพและทดสอบปัจจัยทำนายคุณภาพชีวิตนี้ในผู้ป่วยโรคลำไส้อักเสบในเมืองเหวินโจว ประเทศจีน วิธีการศึกษา: การศึกษาเชิงสัมพันธ์สุ่มตัวอย่างอย่างง่ายผู้ป่วยโรคลำไส้อักเสบ 150 ราย จากแผนกระบบทางเดินอาหารของโรงพยาบาลในเครือแห่งแรกของมหาวิทยาลัยการแพทย์เหวินโจว เมืองเหวินโจว ประเทศจีน ใช้แบบสอบถามรวบรวมข้อมูลทั่วไป และแบบประเมิน 1) คุณภาพชีวิตด้านสุขภาพของผู้ป่วยโรคลำไส้อักเสบ 2) การรับรู้ภาวะสุขภาพ 3) ภาพลักษณ์ทางกาย 4) การรับรู้ความเครียด 5) การรับรู้ด้านการสนับสนุนทางสังคมแบบหลายมิติ ทดสอบความสัมพันธ์ด้วยการวิเคราะห์การถดถอยเชิงเส้นพหุคูณ ผลการศึกษา: ตัวอย่างมีคุณภาพชีวิตด้านสุขภาพของระดับปานกลาง (ค่าเฉลี่ย 86.43 จาก 100 คะแนน) พบว่าการสนับสนุนทางสังคม การรับรู้ภาพลักษณ์ทางกาย การรับรู้ภาวะสุขภาพ และการรับรู้ความเครียด ร่วมกันอธิบายความแปรปรวนของคุณภาพชีวิตด้านสุขภาพอย่างมีนัยสำคัญคิดเป็นร้อยละ 30 (adjusted R2 = 0.300, F4,146 = 16.939, P-value < 0.001) โดยปัจจัยที่มีอำนาจทำนายสูงสุดคือการรับรู้ภาวะสุขภาพ (β = -0.341) ตามด้วยการรับรู้ความเครียด (β = -0.205) การรับรู้ภาพลักษณ์ร่างกาย (β = -0.218) และการสนับสนุนทางสังคม (β = 0.147) (P-value < 0.05 ทั้งหมด) สรุป: คุณภาพชีวิตด้านสุขภาพของคนไข้โรคลำไส้อักเสบชาวจีนมีระดับปานกลาง และสัมพันธ์กับการสนับสนุนทางสังคม การรับรู้ภาพลักษณ์ทางกาย การรับรู้ภาวะสุขภาพ และการรับรู้ความเครียด คำสำคัญ: คุณภาพชีวิตด้านสุขภาพ; โรคลำไส้อักเสบ; ภาพลักษณ์ทางกาย; การรับรู้ภาวะสุขภาพ; การรับรู้ความเครียด; การรับรู้การสนับสนุนทางสังคม Abstract Objective: To determine level of health-related quality of life (HRQOL) and test its predicting factors among patients with inflammatory bowel diseases (IBD) in Wenzhou, China. Methods: This correlational study recruited 150 IBD patients from the Department of Gastroenterology in the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China using simple random sampling method. Demographic characteristics were collected. Questionnaires were used to assess IBD HRQoL, perceived health status, body image, perceived stress, and perceived social support. Associations between HRQoL and its predicting factors were tested using multiple linear regression analysis. Results: HRQOL was at a moderate level (mean = 86.43 out of 110 points). Social support, body image dissatisfaction, perceived health status and perceived stress significantly explained 30.0% of the variance in the HRQOL (adjusted R 2 = 0.300, F4,146 = 16.939, P-value < 0.001). The strongest influencing factor was perceived health status (β= -.341 followed by perceived stress (β = -0.205), body image dissatisfaction (β = -0.218) and social support (β = 0.147) (P-value < 0.05 for all). Conclusion: HRQOL in Chinese IBD patients was at a moderate level and significantly associated with social support, body image dissatisfaction, perceived health status and perceived stress. Keywords: health-related quality of life; inflammatory bowel disease; body image; perceived health status,; perceived stress; perceived social supportDownloads
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ต้นฉบับที่ได้รับการตีพิมพ์ในวารสารนี้ถือเป็นสิทธิ์ของไทยเภสัชศาสตร์และวิทยาการสุขภาพ การนำข้อความใด ๆ ซึ่งเป็นส่วนหนึ่งหรือทั้งหมดของต้นฉบับไปตีพิมพ์ใหม่จะต้องได้รับอนุญาตจากเจ้าของต้นฉบับและวารสารก่อน
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ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความเป็นความรับผิดชอบของผู้นิพนธ์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากเทคนิคการพิมพ์
