Efficacy and Safety of Bumrunglohit (Blood Tonic Pharmacopoeia) with Ferrous Fumarate to Increase Blood Concentration

Abstract

Introduction : This research is a study of Blood tonic formula, which is a drug formula registered in the national list of essential drugs. Objective : The objective of this study is to study the efficacy and safety of a blood tonic formula with ferrous fumarate on increasing blood concentration. Medthod : This is a randomized controlled trial (RCT) with 62 healthy female volunteers at Somdej Phra Phutthalertla Hospital in Samut Songkhram Province are divided into 2 groups: the experimental group who received blood tonic drugs, 31 people, and the control group, who received ferrous fumarate, 31 people, by taking the drug for 30 consecutive days and follow-up with clinical symptoms assessment and blood test results. Results : The results are analyzed by independent t-test and Analysis of Covariance: ANCOVA. Blood concentrations of the group receiving blood tonics and the group receiving ferrous fumarate are not significantly different. As for safety, it is found that blood test results and clinical symptoms assessment before and after receiving the drug are normal. Conclusion : Show that the blood tonic formula effect on the blood concentration level is not different from the modern drug used to treat people with anemia. However, more studies are needed in a larger population or patients with anemia directly and take longer to take the drug. Keyword: Blood tonic formula, ferrous fumarate, blood concentration