การทดสอบเบื้องต้นแบบประเมินผลลัพธ์ด้านการรักษาด้วยการใช้ยาที่ได้จากการรายงานของผู้ป่วยสำหรับคุณภาพชีวิตด้านยาโดยใช้วิธีเชิงผสมผสาน Preliminary Test of the Patient-Reported Outcomes Measure of Pharmaceutical Therapy for Quality of Life (PROMPT-QoL) Using

Abstract

Objective: To preliminarily test PROMPT-QoL (Patient-Reported OutcomesMeasure of Pharmaceutical Therapy for Quality of Life) using mixedmethods based on qualitative (cognitive interviews) and quantitative (aRasch model) approaches. Method: The test of PROMPT-QoL wasconducted with 60 outpatients at King Chulalongkorn Memorial hospitalwho had been using medications for at least 3 months. Cognitive interviewswere used to explore comprehension problems of items, response choices,instructions/formats and other problems. A Rasch model was used toquantitatively identify problems of items and scale layout. Results:According to cognitive interviews, indecision about the cause of impacts ofmedicines and side-effects was the most found problem of PROMPT-QoL.Domain about getting drug information from health care providers wasfound the most found problem, followed by question comprehensionproblem. Eight of 42 questions had infit mean-squares and/or outfit meansquaresbelow 0.7 or above 1.3. Of nine domains, 5 domains had personreliability coefficients below 0.80. Conclusion: Most items of PROMPT-QoLhad favorable fit to the Rasch model. Further studies in large patientgroups are required to test its complete psychometric properties.Keywords: patient-reported outcomes, pretesting, cognitive interviews,Rasch model