Protein Biomarkers in Saliva in Oral Squamous Cell Carcinoma

Authors

  • Bishwa Prakash Bhattarai Department of Oral & Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, 6 Yothi Street, Rachathewee District, Bangkok 10400, Thailand
  • Boworn Klongnoi Department of Oral Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, 6 Yothi Street,Rachathewee District, Bangkok 10400, Thailand
  • Siribang-on Pibooniyom Khovidhunkit Department of Advanced General Dentistry, Faculty of Dentistry, Mahidol University, 6 Yothi Street,Rachathewee District, Bangkok 10400, Thailand
  • Natthamet Wongsirichat Department of Oral Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, 6 Yothi Street,Rachathewee District, Bangkok 10400, Thailand

Abstract

Abstract

Diagnosis of oral squamous cell carcinoma (OSCC) relies mainly on the histopathological analysis of the biopsied tissue which is always traumatic for the patient. Salivary biomarkers might be an important adjunct to the diagnosis of OSCC especially in early stages of the disease because of the ease and non-invasiveness of specimen collection. Many salivary biomarkers have already been introduced. This article is a review of the protein biomarkers that have been investigated for their usefulness in association to OSCC.

Key Words: Oral cancer, biomarker, protein, salivary diagnostics

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Author Biographies

  • Bishwa Prakash Bhattarai, Department of Oral & Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, 6 Yothi Street, Rachathewee District, Bangkok 10400, Thailand
    Master Degree Student
  • Boworn Klongnoi, Department of Oral Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, 6 Yothi Street,Rachathewee District, Bangkok 10400, Thailand
    Lecturer
  • Siribang-on Pibooniyom Khovidhunkit, Department of Advanced General Dentistry, Faculty of Dentistry, Mahidol University, 6 Yothi Street,Rachathewee District, Bangkok 10400, Thailand
    Associate Professor
  • Natthamet Wongsirichat, Department of Oral Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, 6 Yothi Street,Rachathewee District, Bangkok 10400, Thailand
    Professor

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Section

บทความปริทัศน์ (Review articles)

How to Cite

1.
Protein Biomarkers in Saliva in Oral Squamous Cell Carcinoma. SWU Dent J. [Internet]. 2017 Dec. 29 [cited 2026 Oct. 23];10(2):90-102. Available from: https://ejournals.swu.ac.th/swudentj/article/view/9555